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KMID : 0811820070110020288
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Journal of Korean Society of Pediatric Nephrology
2007 Volume.11 No. 2 p.288 ~ p.293
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Two Cases of Thrombotic Thrombocytopenic Purpura in Systemic Lupus Erythematosus
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Kim Hye-Young
Kim Hyung-Hoi
Kim Su-Young
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Abstract
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Thrombotic thrombocytopenic purpura(TTP) is a rare but life-threatening multi-system disorder characterized by the classic pentad of clinical features that includes fever, microangiopathic hemolytic anemia, thrombocytopenia, neurologic abnormalities and renal dysfunction. TTP has been rarely reported to simultaneously present with systemic lupus erythematosus (SLE). While it is important to distinguish between the two diseases of therapeutic implication, cases of concurrent TTP and SLE help to elucidate the pathophysiology that underlies each condition. We describe two adolescents with synchronous TTP and SLE, and review the literature.
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KEYWORD
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Thrombotic thrombocytopenic purpura, Systemic lupus erythematosus, Plasmapheresis
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